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October 28, 2026CompoundingHHS lets 503A pharmacies compound six peptides under an interim enforcement discretion policyOctober 28, 2026Trial resultRetatrutide beats Ozempic on blood sugar and weight in head-to-head TRANSCEND-T2D-2 trialOctober 23, 2026FDA approvalFDA extends once-weekly insulin icodec (Awiqli) to children 10 and older with type 2 diabetesOctober 21, 2026CompoundingCitizen petition asks FDA not to allow compounding of seven peptides reviewed by its advisory committeeOctober 1, 2026Trial resultSurvodutide SYNCHRONIZE-2 phase 3 results in obesity with type 2 diabetes published in NEJMSeptember 30, 2026Trial resultEloraTZP (eloralintide plus tirzepatide) phase 2 results presented at EASD 2026September 30, 2026Trial resultOrforglipron ACHIEVE-4 cardiovascular safety trial published in The LancetSeptember 29, 2026Trial resultFull TRIUMPH-2 retatrutide results published in The LancetSeptember 24, 2026FDA approvalFDA approves insulin efsitora alfa (Onswik), a once-weekly basal insulin for type 2 diabetesSeptember 21, 2026WADAWADA publishes 2027 Prohibited List, naming peptides as examples of non-approved substances

October 28, 2026CompoundingHHS lets 503A pharmacies compound six peptides under an interim enforcement discretion policyOctober 28, 2026Trial resultRetatrutide beats Ozempic on blood sugar and weight in head-to-head TRANSCEND-T2D-2 trialOctober 23, 2026FDA approvalFDA extends once-weekly insulin icodec (Awiqli) to children 10 and older with type 2 diabetesOctober 21, 2026CompoundingCitizen petition asks FDA not to allow compounding of seven peptides reviewed by its advisory committeeOctober 1, 2026Trial resultSurvodutide SYNCHRONIZE-2 phase 3 results in obesity with type 2 diabetes published in NEJMSeptember 30, 2026Trial resultEloraTZP (eloralintide plus tirzepatide) phase 2 results presented at EASD 2026September 30, 2026Trial resultOrforglipron ACHIEVE-4 cardiovascular safety trial published in The LancetSeptember 29, 2026Trial resultFull TRIUMPH-2 retatrutide results published in The LancetSeptember 24, 2026FDA approvalFDA approves insulin efsitora alfa (Onswik), a once-weekly basal insulin for type 2 diabetesSeptember 21, 2026WADAWADA publishes 2027 Prohibited List, naming peptides as examples of non-approved substances

Peptide CompendiumLanguageSign in

Blend or stack

CJC-1295 + Ipamorelin

Also called Mod GRF + Ipamorelin

Pairs a GHRH analog with a ghrelin-receptor agonist, the two main ways to push the pituitary to release growth hormone.

What is in it

Growth hormone axisEarly human dataFlashcard

CJC-1295

CJC-1295 with DAC · CJC-1295 without DAC

CJC-1295 is a lab-made, modified version of the active part of growth-hormone-releasing hormone.

Growth hormone axisEarly human dataFlashcard

Ipamorelin

Ipamorelin acetate · NNC 26-0161

Ipamorelin is a small lab-made peptide (five building blocks) that copies the hunger hormone ghrelin to make the pituitary release growth hormone.

Is there evidence for the combination?

The idea of combining the two drug types comes from a 1990 study in healthy men. A single injection of a GHRP together with GHRH released more growth hormone than either alone ¹. That study used GHRP-6 and natural GHRH, not CJC-1295 or ipamorelin, and we found no trial of this exact pair.

Each ingredient at a glance

Ingredient	Evidence	US FDA status	Sports (WADA)
CJC-1295	Early human data	Not FDA-approved; development discontinued	Prohibited at all times (S2.2.4 GHRH and analogues; CJC-1295 named)
Ipamorelin	Early human data	Not FDA-approved	Prohibited at all times (S2.2.4 growth hormone secretagogues; named)

Mixing adds unknowns. A blend carries the risks of every ingredient, and the interactions are untested. Vial contents and ratios are set by sellers and are not standardized. See each ingredient page for safety and legal details.

Sources

Bowers CY et al. GH-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab 1990;70(4):975