Hormonal & reproductive

Prostamax

Also called ProstaMax, KEDP peptide, Lys-Glu-Asp-Pro, prostate peptide bioregulator

Prostamax is a small lab-made peptide (four amino acids) from Vladimir Khavinson's Russian 'peptide bioregulator' series, named for the prostate. Online sellers promote it for enlarged prostate, but the published research is mainly lab work on chromosomes in blood cells. In June 2026 the FDA warned a US seller that Prostamax marketed with prostate claims is an unapproved new drug.

Preclinical onlyStudied in cells or animals only. Effects in people are unknown.

All printable flashcards

Drawn from its published sequence: 4 residues, one bead each.

Overview

How it works

Proposed, not established. In cultured lymphocytes from elderly people, Prostamax loosened condensed chromatin, including structural heterochromatin near the centromere of chromosome 1, which the authors interpret as reactivating age-silenced genes ²³⁴. No study verified here shows a direct effect on prostate tissue or urinary symptoms in people.

What research shows

Cell study (lymphocytes from donors aged 75–88, 2004): Prostamax activated ribosomal genes and decondensed pericentromeric heterochromatin on chromosome 1 ².
Cell studies (human lymphocytes, 2004 and 2012): KEDP induced 'deheterochromatinization' (unpacking) of chromatin in cells from old individuals ⁴³.
No controlled human trial of Prostamax for prostate enlargement or prostatitis was verified in this review.
Research comes almost entirely from the Khavinson group and its collaborators.

Doses studied in people

No verified dose from a published controlled human trial; doses circulating online are not trial-derived.

Read this first: these are the amounts given to participants in published studies or written on official prescribing labels, reported for reference. They are not recommendations. Trial doses were chosen for specific patients under medical supervision, and a dose that is safe in one person can be harmful in another.

Vial math

Many research vials hold 5 or 10 mg of powder. This table shows how much ends up in each mark on a U-100 insulin syringe for common amounts of added liquid. It is arithmetic only, not a dose.

Vial	Liquid added	Concentration	Per unit (0.01 mL)
5 mg	1 mL	5 mg/mL	50 mcg	Open in calculator
5 mg	2 mL	2.5 mg/mL	25 mcg	Open in calculator
5 mg	3 mL	1.67 mg/mL	16.7 mcg	Open in calculator
10 mg	1 mL	10 mg/mL	100 mcg	Open in calculator
10 mg	2 mL	5 mg/mL	50 mcg	Open in calculator
10 mg	3 mL	3.33 mg/mL	33.3 mcg	Open in calculator

More sizes: all vial sizes · How this works: Syringes and units · Reconstitution guide.

Safety

No formal human safety studies have been published; long-term safety is unknown.
FDA noted that injectable unapproved products like those in its 2026 warning letter pose particular public-health risks ⁵.
Unregulated 'research' products may vary in purity, sequence and content.

Report side effects of any drug or product to the FDA through MedWatch. For a possible poisoning in the US, call Poison Control at 1-800-222-1222.

Legal status

FDA: Not FDA-approved. FDA warning letter to Wholesale Peptide (June 17, 2026) states Prostamax sold with claims such as treating enlarged prostate (BPH) and improving bladder control is an unapproved new drug, and that 'research use only' labeling does not change this ⁵.
Compounding: Not listed in any category of FDA's 503A bulk drug substance nominations (list updated May 14, 2026), so it has no recognized route for US pharmacy compounding ⁷.
Sports (WADA): Not named on the 2026 List. If it has no current government approval as a human medicine anywhere, it would fall under S0 (non-approved substances, prohibited at all times). Confirm with your anti-doping organization ⁸.
Other: Developer material claims Russian Ministry of Health adoption ⁶; no current Russian drug registration was verified in this review.

Rules change often. See Legal status of peptides for how these categories work.

History

Developed at the St. Petersburg Institute of Bioregulation and Gerontology; the institute's own material lists it among five synthetic peptides it says were adopted by the Russian Ministry of Health, a claim not independently verified ⁶. Chromatin studies were published in 2004–2012 ²³⁴. On June 17, 2026, FDA issued a warning letter to the US seller Wholesale Peptide over Prostamax and Gonadorelin ⁵.

Common questions

Is Prostamax approved for enlarged prostate (BPH)?

No. In a June 2026 warning letter, FDA called Prostamax sold with BPH and bladder-control claims an unapproved new drug ⁵.

What does the research show?

Mostly lab studies showing chromatin changes in blood cells from elderly people ²³. No controlled human trials for prostate conditions were verified.

Is Prostamax banned in sport?

It is not named on WADA's 2026 list, but non-approved substances generally fall under S0, prohibited at all times ⁸.

What are the known risks?

Human safety has not been formally studied. FDA has flagged injectable unapproved peptide products as a particular public-health risk ⁵.

Related compounds

Hormonal & reproductivePreclinical onlyFlashcard

Testagen

KEDG peptide · Lys-Glu-Asp-Gly

Testagen is a small lab-made peptide (four amino acids) from Vladimir Khavinson's Russian 'peptide bioregulator' series, named for the testes and marketed online for male hormonal health.

Longevity & mitochondrialPreclinical onlyFlashcard

Livagen

KEDA peptide · Lys-Glu-Asp-Ala

Livagen is a small lab-made peptide (four amino acids) from Vladimir Khavinson's Russian 'peptide bioregulator' series, named for the liver.

Immune & antimicrobialEarly human dataFlashcard

Vilon

KE dipeptide · Lys-Glu

Vilon is the smallest of Vladimir Khavinson's Russian 'peptide bioregulators': just two amino acids (lysine and glutamic acid).

Longevity & mitochondrialPreclinical onlyFlashcard

Epitalon

epithalon · epithalone

Epitalon is a tiny four-amino-acid peptide made in the lab, modeled on an extract from the pineal gland.

Sources

Last reviewed 2026-10-26 · How we research · Found an error? See our corrections policy.